2016年5月9日星期一
Big news: The medical team of Fuda Cancer Hospital removed a giant abdominal tumor weighing up to 6.1kg for a female patient
On April 20, 2016, the medical team of Guangzhou Fuda Cancer Hospital created a miracle of life once again. After eight hours’ hard work, the medical team at Fuda Cancer Hospital completed a complicated operation-they removed the giant abdominal liomyoma for a young female. The largest mass removed, weighing over 6kg, is bigger than two footballs.
The medical team of Fuda Cancer Hospital Haizhu Branch successfully removed a giant abdominal tumor for a female patient
A women with giant abdomen walked into the office of President Xu Kecheng
In the morning of March 25, 2016, a “heavily pregnant” woman, accompanied by her family members, walked into the office of Xu Kecheng, Chief President of Fuda Cancer Hospital. The patient surnamed Lin, 29 years old, is from Lianjiang, Guangdong. She told President Xu that she was not pregnant; instead there was a big tumor in her abdomen. She could feel that the tumor was still growing and she was having breathing difficulty. She entreated Fuda Cancer Hospital to help her.
After studied Ms. Lin’s examination result, Prof. Xu Kecheng was shocked as the abdominal tumor was so big that it has occupied her whole abdominal cavity. The organs in abdominal cavity were heavily compressed. The patient was having breathing difficulty, urination difficulty, hydronephrosis, injured renal function and edema in the lower limbs. Due to long-term consumption of tumor, she was emaciated and pale but her eyes revealed her desire for life.
“President Xu, doctors at the local hospital and several major hospitals in Guangzhou said I cannot get operated. Please help me. I’ve got to stay alive because I have two kids to look after...”
Looking at the patient with a giant abdominal tumor reminds President Xu Kecheng of these patients with giant abdominal tumor who have been successfully treated at FUDA. They are Peng Ximei, Bingbing, etc. He decided to challenge the impossible once again and try all out to help her.
At noon on the same day, Ms. Lin was sent to Fuda Cancer Hospital Haizhu Branch and was admitted for postoperative recurrence of abdominal liomyoma.
The nightmare started three years ago
Ms. Lin is from Heliao town, Lianjiang City, Guangdong Province. In December 2013, Ms. Lin, 26 years old, felt abdominal distention accompanied by dull pain. She did ultrasound and CT scan at the affiliated hospital of Hainan Medical University and was found to have an enormous space-occupying lesion in the abdomen, which was suspected to be benign tumor. Then she underwent tumorectomy. The pathological result showed (abdominal wall) gastrointestinal mesenchymal tumor, likely to be liomyoma. After the operation, she had paroxysmal left lower abdominal pain occasionally, but she did not pay any attention to it. In October 2015, she was found to have mass in the previous tumor bed during her re-examination. Tumor recurrence was detected and the tumor was growing rapidly.
Ms. Lin was very afraid. She was even dreading to imagine what the consequences would be if the tumor continued to grow. The nightmare had been hanging over her and her family members.
“Maybe I consult with some major hospitals in Guangzhou.” it suddenly occurred to her.
However, things did not go well as they thought. They consulted several major hospitals in Guangzhou, but doctors all said that the tumor was too big to be resected.
She saw a glimmer of hope after being admitted by FUDA
As the tumor grew bigger, she started to have such symptoms as constipation and dysuria. Her husband proposed, “We may go to Beijing and have a try. There will always be a way out.” When Ms. Lin was hesitating the next step forward, what her mother-in-law said caught her attention “Several days ago, I watched a TV program. It tells about how a hospital successfully treated a girl who have giant abdominal tumor. I remember the hospital is called Fuda Cancer Hospital. “Should we have a try in that hospital?” Ms. Lin agreed to her mother-in-law’s proposal and come to Guangzhou Fuda Cancer Hospital with her family. On March 25, Ms. Lin was admitted into Fuda Cancer Hospital Haizhu Branch.
Face up to the difficulty
Ms. Lin completed relevant examination upon admission. The findings of CT scan are as follows: postoperative recurrence of abdominal liomyoma is considered; adjacent intestines, bladder and uterus are compressed and adhered; the inferior pole of left kidney is compressed; bilateral ureters are compressed and narrowed. The abdominal aorta and bilateral illiac arteries and veins are compressed; small nodular lesions are noted in the inferior lobe of right lung; hydronephrosis is noted in bilateral pelvises and the superior segment of ureter and the left side is more significant, which are considered to be caused by the compression of the middle-lower segment of both lower ureters; the left kidney is enlarged; the left kidney function is damaged; varicosity is noted in the space between the inferior margin of spleen and the abdominal mass; varicosity is noted in pelvic cavity...ECG test showed sinus bradycardia.
As the tumor showed rapid progression, Ms. Lin had difficult defecation. Patient’s symptoms together with the erect abdominal plain radiograph showed the possibility of incomplete intestinal obstruction.
The Vice President Li Haibo, Chief Physician Wang Jiannan, Visiting Doctor Zhou Zhanchun, Visiting Doctor Leng Yin, Resident Doctor Lin Qiongmei, Resident Doctor Li Chunli made an in-depth study on Ms. Lin’s condition and held preoperative discussion.
Prof. Wang Jiannan noted that the operation carries four major risks:
1. The surgical incision will be very hard to heal since the tumor is too big and needs to be fully exposed during the operation;
2. There isn’t a clear demarcation between the tumor and adjacent organs and tissues. The adjacent blood vessels, kidney, ureters, intestines, uterus, and bilateral adnexa might be easily injured; hence, revascularization, colostomy, pyelostomy might be done during the operation;
3. The postoperative recurrence rate is high and repeated operation may need to be done due to incomplete resection of tumor;
4. The risk of intraoperation massive haemorrhage is high; hence, abundant blood product should be prepared. The chance of having extensive intestinal adhesion is high; hence, anti-adhesion treatment needs to be done before closing the abdominal cavity.
Dr. Li Haibo noted that the giant abdominal tumor is compressing important visceral organs such as heart, blood vessels, kidneys and intestines, causing functional disturbance. Patient will die of multiple organ failure if the operation cannot be done. Other treatments, such as radiotherapy, chemotherapy, mini-invasive ablation are of no help to the patient. Only surgical resection of tumor can save the patient’s life. Fortunately, the tumor is only compressing not invading the important organs in the abdominal cavity. Impaired renal function is caused by urination difficulty that is caused by tumor compression. The impaired renal function can be reversed if the compression is relieved. He mentioned that considering that the patient can tolerate major operation as she was at her prime and the level of tumor malignancy was not high, the patient had the opportunity to have the tumor resected and enjoy a long-term surviving. Though the operation carries great risk, the reward was worth the risk as long as adequate preoperative operation was made.
The anesthetist Fang Gang believed that the reward of the operation was worth its risk. The consequence would be fatal if operation was not done at an early date.
After three rounds of discussion, the medical team of Fuda Cancer Hospital decided to do the following procedures for the patient: bilateral ureter stenting+exploratory laparotomy+abdominal tumor resection+colostomy. The operation was scheduled to take place on April 20.
The giant tumor is removed
After the attending doctor explained to Ms. Lin and her family member the operation plan and the possible risks entailed, Ms. Lin said, “I don’t have any way out. I want to have a try regardless.”
At 8:00a.m., of April 20, Ms. Lin was wheeled into the operation room. The operation room was in tension. The surgeons were Prof. Wang Jiannan and Vice President Li Haibo; the assistants were Zhou Zhanchun and Leng Yin. Anesthesiologist Fang Gang was in charge of intraoperative management.
As expected, the giant tumor was found to have occupied the abdominal cavity and it’s impossible to have a full view of the tumor after the abdominal wall was cut open. A slight move would cause bleeding as the tumor was rich in blood vessels. Shortly after the operation began, the amount of bleeding reached about 1,000ml. The operation was a big test of perseverance and courage to the surgeons. The surgeons, bold but cautious, exposed the tumor while stopping bleeding. The anesthesiologist and the surgeons acted in close coordination. The anesthesiologist kept the surgeons informed of the patient’s vital signs and gave timely blood transfusion and fluid infusion to patients, which have bought more time for surgeons.
The operation was ongoing: to separate abdominal wall adhesion, to separate angiosynizesis, to separate ureter adhesion, to separate bladder adhesion, to separate intestinal adhesion, to remove part of the invaded intestine, to do intestinal anastomosis, to do hemostasis by ligation, in the end, to do colostomy. Unconsciously, eight hours passed, with the concerted effort of all medical staff, the tumor was finally removed.
It took a dozen of operation staffs eight hours to complete the operation. The amount of bleeding, blood transfusion, blood plasma, platelet, albumin were 6,300ml, 5,000mg, 3,000ml, 1 mechanical production unit, 90g respectively. A total of over 10,000ml infusion and transfusion were made. The largest mass removed weighed up to 6.1kg. These startling figures represent the return of a life.
When Prof. Wang Jiannan walked out of the operation room, he took a deep breath and said to the patient’s family, “The operation is very successful. The patient has had stable vital signs throughout the operation. Please rest assured.”
When Dr. Li Haibo showed the removed mass to the patient’s family members, they were full of surprise, happiness and appreciation. They never thought that there was such a big mass in the patient’s abdomen. They are so amazed that the tumor that was deemed to be unresectable by the nationally renowned hospitals is removed at Fuda Cancer Hospital. They are so happy that the patient’s life gets extended. They are even more grateful for the respect that the medical team of Fuda Cancer Hospital has shown to life.
At 10p.m., five hours after the operation, Ms. Lin, who was still on respirator has been wide awake from operation in the ICU. Her vital signs were stable and intraperitoneal drainage was becoming less. After completing relevant examinations, Li Haibo, the Vice President of FUDA, removed her tracheal intubation, which means that her life was out of danger. He said, “We are greatly relieved to see that she has pulled through the difficult situation and is having stable vital signs now. What we have done have been very rewarding. ”
The medical team of Fuda Cancer Hospital Haizhu Branch successfully removed a giant abdominal tumor for a female patient
A women with giant abdomen walked into the office of President Xu Kecheng
In the morning of March 25, 2016, a “heavily pregnant” woman, accompanied by her family members, walked into the office of Xu Kecheng, Chief President of Fuda Cancer Hospital. The patient surnamed Lin, 29 years old, is from Lianjiang, Guangdong. She told President Xu that she was not pregnant; instead there was a big tumor in her abdomen. She could feel that the tumor was still growing and she was having breathing difficulty. She entreated Fuda Cancer Hospital to help her.
After studied Ms. Lin’s examination result, Prof. Xu Kecheng was shocked as the abdominal tumor was so big that it has occupied her whole abdominal cavity. The organs in abdominal cavity were heavily compressed. The patient was having breathing difficulty, urination difficulty, hydronephrosis, injured renal function and edema in the lower limbs. Due to long-term consumption of tumor, she was emaciated and pale but her eyes revealed her desire for life.
“President Xu, doctors at the local hospital and several major hospitals in Guangzhou said I cannot get operated. Please help me. I’ve got to stay alive because I have two kids to look after...”
Looking at the patient with a giant abdominal tumor reminds President Xu Kecheng of these patients with giant abdominal tumor who have been successfully treated at FUDA. They are Peng Ximei, Bingbing, etc. He decided to challenge the impossible once again and try all out to help her.
At noon on the same day, Ms. Lin was sent to Fuda Cancer Hospital Haizhu Branch and was admitted for postoperative recurrence of abdominal liomyoma.
The nightmare started three years ago
Ms. Lin is from Heliao town, Lianjiang City, Guangdong Province. In December 2013, Ms. Lin, 26 years old, felt abdominal distention accompanied by dull pain. She did ultrasound and CT scan at the affiliated hospital of Hainan Medical University and was found to have an enormous space-occupying lesion in the abdomen, which was suspected to be benign tumor. Then she underwent tumorectomy. The pathological result showed (abdominal wall) gastrointestinal mesenchymal tumor, likely to be liomyoma. After the operation, she had paroxysmal left lower abdominal pain occasionally, but she did not pay any attention to it. In October 2015, she was found to have mass in the previous tumor bed during her re-examination. Tumor recurrence was detected and the tumor was growing rapidly.
Ms. Lin was very afraid. She was even dreading to imagine what the consequences would be if the tumor continued to grow. The nightmare had been hanging over her and her family members.
“Maybe I consult with some major hospitals in Guangzhou.” it suddenly occurred to her.
However, things did not go well as they thought. They consulted several major hospitals in Guangzhou, but doctors all said that the tumor was too big to be resected.
She saw a glimmer of hope after being admitted by FUDA
As the tumor grew bigger, she started to have such symptoms as constipation and dysuria. Her husband proposed, “We may go to Beijing and have a try. There will always be a way out.” When Ms. Lin was hesitating the next step forward, what her mother-in-law said caught her attention “Several days ago, I watched a TV program. It tells about how a hospital successfully treated a girl who have giant abdominal tumor. I remember the hospital is called Fuda Cancer Hospital. “Should we have a try in that hospital?” Ms. Lin agreed to her mother-in-law’s proposal and come to Guangzhou Fuda Cancer Hospital with her family. On March 25, Ms. Lin was admitted into Fuda Cancer Hospital Haizhu Branch.
Face up to the difficulty
Ms. Lin completed relevant examination upon admission. The findings of CT scan are as follows: postoperative recurrence of abdominal liomyoma is considered; adjacent intestines, bladder and uterus are compressed and adhered; the inferior pole of left kidney is compressed; bilateral ureters are compressed and narrowed. The abdominal aorta and bilateral illiac arteries and veins are compressed; small nodular lesions are noted in the inferior lobe of right lung; hydronephrosis is noted in bilateral pelvises and the superior segment of ureter and the left side is more significant, which are considered to be caused by the compression of the middle-lower segment of both lower ureters; the left kidney is enlarged; the left kidney function is damaged; varicosity is noted in the space between the inferior margin of spleen and the abdominal mass; varicosity is noted in pelvic cavity...ECG test showed sinus bradycardia.
As the tumor showed rapid progression, Ms. Lin had difficult defecation. Patient’s symptoms together with the erect abdominal plain radiograph showed the possibility of incomplete intestinal obstruction.
The Vice President Li Haibo, Chief Physician Wang Jiannan, Visiting Doctor Zhou Zhanchun, Visiting Doctor Leng Yin, Resident Doctor Lin Qiongmei, Resident Doctor Li Chunli made an in-depth study on Ms. Lin’s condition and held preoperative discussion.
Prof. Wang Jiannan noted that the operation carries four major risks:
1. The surgical incision will be very hard to heal since the tumor is too big and needs to be fully exposed during the operation;
2. There isn’t a clear demarcation between the tumor and adjacent organs and tissues. The adjacent blood vessels, kidney, ureters, intestines, uterus, and bilateral adnexa might be easily injured; hence, revascularization, colostomy, pyelostomy might be done during the operation;
3. The postoperative recurrence rate is high and repeated operation may need to be done due to incomplete resection of tumor;
4. The risk of intraoperation massive haemorrhage is high; hence, abundant blood product should be prepared. The chance of having extensive intestinal adhesion is high; hence, anti-adhesion treatment needs to be done before closing the abdominal cavity.
Dr. Li Haibo noted that the giant abdominal tumor is compressing important visceral organs such as heart, blood vessels, kidneys and intestines, causing functional disturbance. Patient will die of multiple organ failure if the operation cannot be done. Other treatments, such as radiotherapy, chemotherapy, mini-invasive ablation are of no help to the patient. Only surgical resection of tumor can save the patient’s life. Fortunately, the tumor is only compressing not invading the important organs in the abdominal cavity. Impaired renal function is caused by urination difficulty that is caused by tumor compression. The impaired renal function can be reversed if the compression is relieved. He mentioned that considering that the patient can tolerate major operation as she was at her prime and the level of tumor malignancy was not high, the patient had the opportunity to have the tumor resected and enjoy a long-term surviving. Though the operation carries great risk, the reward was worth the risk as long as adequate preoperative operation was made.
The anesthetist Fang Gang believed that the reward of the operation was worth its risk. The consequence would be fatal if operation was not done at an early date.
After three rounds of discussion, the medical team of Fuda Cancer Hospital decided to do the following procedures for the patient: bilateral ureter stenting+exploratory laparotomy+abdominal tumor resection+colostomy. The operation was scheduled to take place on April 20.
The giant tumor is removed
After the attending doctor explained to Ms. Lin and her family member the operation plan and the possible risks entailed, Ms. Lin said, “I don’t have any way out. I want to have a try regardless.”
At 8:00a.m., of April 20, Ms. Lin was wheeled into the operation room. The operation room was in tension. The surgeons were Prof. Wang Jiannan and Vice President Li Haibo; the assistants were Zhou Zhanchun and Leng Yin. Anesthesiologist Fang Gang was in charge of intraoperative management.
As expected, the giant tumor was found to have occupied the abdominal cavity and it’s impossible to have a full view of the tumor after the abdominal wall was cut open. A slight move would cause bleeding as the tumor was rich in blood vessels. Shortly after the operation began, the amount of bleeding reached about 1,000ml. The operation was a big test of perseverance and courage to the surgeons. The surgeons, bold but cautious, exposed the tumor while stopping bleeding. The anesthesiologist and the surgeons acted in close coordination. The anesthesiologist kept the surgeons informed of the patient’s vital signs and gave timely blood transfusion and fluid infusion to patients, which have bought more time for surgeons.
The operation was ongoing: to separate abdominal wall adhesion, to separate angiosynizesis, to separate ureter adhesion, to separate bladder adhesion, to separate intestinal adhesion, to remove part of the invaded intestine, to do intestinal anastomosis, to do hemostasis by ligation, in the end, to do colostomy. Unconsciously, eight hours passed, with the concerted effort of all medical staff, the tumor was finally removed.
The largest mass removed weighs up to 6.135kg
It took a dozen of operation staffs eight hours to complete the operation. The amount of bleeding, blood transfusion, blood plasma, platelet, albumin were 6,300ml, 5,000mg, 3,000ml, 1 mechanical production unit, 90g respectively. A total of over 10,000ml infusion and transfusion were made. The largest mass removed weighed up to 6.1kg. These startling figures represent the return of a life.
When Prof. Wang Jiannan walked out of the operation room, he took a deep breath and said to the patient’s family, “The operation is very successful. The patient has had stable vital signs throughout the operation. Please rest assured.”
When Dr. Li Haibo showed the removed mass to the patient’s family members, they were full of surprise, happiness and appreciation. They never thought that there was such a big mass in the patient’s abdomen. They are so amazed that the tumor that was deemed to be unresectable by the nationally renowned hospitals is removed at Fuda Cancer Hospital. They are so happy that the patient’s life gets extended. They are even more grateful for the respect that the medical team of Fuda Cancer Hospital has shown to life.
At 10p.m., five hours after the operation, Ms. Lin, who was still on respirator has been wide awake from operation in the ICU. Her vital signs were stable and intraperitoneal drainage was becoming less. After completing relevant examinations, Li Haibo, the Vice President of FUDA, removed her tracheal intubation, which means that her life was out of danger. He said, “We are greatly relieved to see that she has pulled through the difficult situation and is having stable vital signs now. What we have done have been very rewarding. ”
Xu Kecheng, the Chief President of FUDA, visiting Ms. Lin
2016年4月21日星期四
Fuda Cancer Hospital-Guangzhou: A Brief Introduction of FUDA
Fuda Cancer Hospital-Guangzhou: A Brief Introduction of FUDA: FUDA Cancer Hospital, located in Guangzhou, Guangdong province, consisted of two regions including one in Tianhe District(located in the 2n...
2016年4月8日星期五
The New Technology Could Bring Benefits to Cancer Patients if the Tumor is Identified
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| Ms. Gurli, a 68-year-old Danish anti-cancer celebrity |
“To know others having cancer is one thing, but to know yourself having cancer is another thing. My world was almost collapsed when I got to know my diagnosis.” Ms. Gurli, a retired Danish teacher said when she was sharing her experience of “living with cancer”. It~s hard to tell that she has been a 68-year-old cancer patient from her energetic demeanor. In 2008, her Danish doctor claimed that “she only had three to four months to live whatever treatments she would receive”. What it is that has made her such an active and humorous person 8 years later.
In the morning of March 16, 2016, Guangzhou Fuda Cancer Hospital held a special experience sharing meeting, on which the cancer patient Ms. Gurli, the 100th patient who has underwent NanoKnife illustrated to the attendants the success of NanoKnife with her own experience. It is known that conventional resection operation would inflict great physical trauma to cancer patient; it makes cancer patients even more painful to undergo radiotherapy and chemotherapy. Moreover, resection operation would often inflict irreversible damage to normal tissues, blood vessels and nerve system in particular. The physical trauma and damage would adversely affect postoperative recovery and the living quality of patient. Hence, in the face of treatment, cancer patients have more fears to the operative wound and the trauma that might be caused by resection operation. Fortunately, we are pleased to see the application of a latest treatment modality for cancer that is NanoKnife. According to Prof. Niu, Executive President of Guangzhou Fuda Cancer Hospital, during the procedure of NanoKnife, high electric-field and ultrashort pulses are given to destroy lipid bilayer structure of cancer cell membrane and form numerous irreversible nano-sized pores in the cell membrane. Cell membrane permeability will be changed to allow molecules of different sizes free access to cells, which will lead to cell death. Apoptotic tumor cells will be consumed by immune cells as their antigens are exposed. The zone where tumor was located will be replaced by normal cells and resume normal function gradually. In short, NanoKnife is a mini-invasive, harmless or low harm, precise and effective method for tumor inactivation. The most distinctive feature of NanoKnife is that it can preserve the normal tissues and structures in the targeted area in a non-invasive way so as to create favorable conditions for the blood vessels, nerve tissues in the ablated area to restore their normal function. Ms. Gurli underwent NanoKnife for the multiple neuroendocrine neoplasms in liver on March 8, 2016. She was full of spirit and energy and was able to walk and talk like a normal person when we met her at the experience sharing meeting. Such a fast postoperative recovery can never be seen in traditional resection operation.
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| Dr. Lu Mingying, the Rank Prize winner and Chinese scientist shared with the attendants her successful treatment experience |
Another special patient also presented at the experience sharing meeting. She is Dr. Lu Mingying, the Rank Prize winner and Chinese scientist. She learned of NanoKnife on the internet. She noted, “I searched on the internet with NanoKnife as the keyword and found Guangzhou Fuda Cancer Hospital in the end. I made several phone calls to FUDA and learned that FUDA has completed over 70 cases of NanoKnife at that time. I believe that NanoKnife has been well developed at FUDA and I made the decision to FUDA to receive NanoKnife.” Prof. Niu said, “She could not walk due to intense abdominal pain and abdominal distension upon admission.” Dr. Lu Mingying underwent NanoKnife at FUDA on February 2, 2016. She had her symptoms alleviated significantly and was able to walk on February 6. It is reported that NanoKnife is applicable to liver cancer, lung cancer, kidney cancer, prostate cancer and other solid cancers. It has distinctive advantage in treating tumors that is close to hepatic hilus, gallbladder bile duct, pancreas, and ureter. Moreover, over half cases of NanoKnife in China are completed at Fuda Cancer Hospital.
Xu Kecheng, Chief President of Guangzhou Fuda Cancer Hospital noted that over the past ten years, Fuda Cancer Hospital has been committing to treat advanced cancer--a difficult medical problem in the world with “3C+P” treatment model dominated by cryosurgical ablation (CSA), cancer microvascular intervention (CMI) and combined immunotherapy for cancer (CIC) with an aim of prolonging patients~ life and improving their quality of life. FUDA has been leading the world in terms of the number of cases and types of cancer that CSA has treated; FUDA has also made breakthrough achievements in treating central lung cancer, great hepatic carcinoma, and pancreatic cancer with CSA, which has won several awards for FUDA at home and abroad. In June, 2015, FUDA introduced NanoKnife equipment from America and carried out the first NanoKnife on pancreatic cancer in mainland China on July 2, 2015. As of now, FUDA has completed 100 cases of NanoKnife, the number of which ranks the first in China.
On the same day, Guangzhou Fuda Cancer Hospital and BGI Group signed a strategic alliance agreement. FUDA-BGI strategic alliance allows experts on both sides to carry out concrete discussion on the cooperation vision and feasibility of the building and application of tumor sample data base, tumor detection at molecular level and the screening and early warning of high risk group by combining cancer high incidence scene and high-throughput sequencing.
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